Single Biggest Cancer Dictionary in the World
What is IRDye800CW-labeled heptapeptide KSP-910638G?
Pronunciation: /irdye* eɪt ˈhənərd cw* ˈleɪbəld heptapeptide* ksp* naɪn ˈhənərd ənd tɛn ˈθaʊzənd, sɪks ˈhənərd ənd thirty-eight* ʤi/
IRDye800CW-labeled heptapeptide KSP-910638G
Definition
An imaging agent composed of a heptapeptide targeting human epithelial growth factor receptor type 2 (EGFR2; HER2; ErbB2) conjugated, via a five-amino acid linker, to the near-infrared (NIR) fluorescent dye IRDye800CW, that can potentially be used for the imaging of HER2-expressing tumors. Upon oral administration of the IRDye800CW-labeled heptapeptide KSP-910638G, the peptide moiety targets and binds to HER2 expressed on tumor cells in the gastrointestinal (GI) tract. Upon fluorescence imaging of the fluorophore IRDye800CW, the tumor cells can be detected.