Single Biggest Cancer Dictionary in the World

What is

glioma-associated peptide-loaded dendritic cell vaccine SL-701

?

Pronunciation: /glioma* əˈsoʊʃiˌeɪtəd ˈpɛpˌtaɪd ˈloʊdɪd dɛnˈdrɪtɪk sɛl ˌvækˈsin sl* ˈsɛvən ˈhənərd ənd wən/

glioma-associated peptide-loaded dendritic cell vaccine SL-701

Definition

A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis.