Definition

A deuterium metabolic imaging (DMI) agent composed of glucose labeled with the non-radioactive deuterium (2H, D) isotope, with potential metabolic imaging activity upon magnetic resonance spectroscopy. Upon administration of deuterated glucose, the glucose is metabolized, and both the deuterium-labeled glucose and the deuterium-containing metabolites can be imaged by magnetic resonance spectroscopy. Since some tumor cells metabolize glucose faster and through different pathways than normal cells, this agent may help assess metabolic tumor pathways, tumor burden and response to treatment.