Single Biggest Cancer Dictionary in the World
What is c-Met inhibitor JNJ-38877605?
Pronunciation: /si mɛt ˌɪnˈhɪbətər jnj* thirty-eight* ˈmɪljən, eɪt ˈhənərd ənd seventy-seven* ˈθaʊzənd, sɪks ˈhənərd ənd faɪv/
c-Met inhibitor JNJ-38877605
Definition
An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. c-Met inhibitor JNJ-38877605 selectively inhibits c-Met, a receptor tyrosine kinase (RTK) involved in cancer cell survival and invasiveness, and tumor angiogenesis. c-Met is also known as hepatocyte growth factor receptor (HGFR).