Single Biggest Cancer Dictionary in the World
What is
autologous dendritic cell-tumor fusion vaccine
?Pronunciation: /autologous* dɛnˈdrɪtɪk sɛl ˈtumər fˈjuʒən ˌvækˈsin/
autologous dendritic cell-tumor fusion vaccine
Definition
A therapeutic cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous tumor cells with potential immunostimulatory and antineoplastic activities. Autologous dendritic cell-tumor fusion vaccine is generated in vitro by mixing DCs and irradiated tumor cells harvested from individual patients and treating them with polyethylene glycol (PEG) to produce DC-tumor cell fusion hybrid cells. Upon administration, autologous dendritic cell-tumor fusion vaccine may elicit antitumor humoral and cellular immune responses.