Single Biggest Cancer Dictionary in the World
What is autologous cytomegalovirus-specific cytotoxic T lymphocytes?
Pronunciation: /autologous* ˌsaɪtəˌmɛgəloʊˈvaɪrəs spɪˈsɪfɪk cytotoxic* ti ˈlɪmfəˌsaɪts/
autologous cytomegalovirus-specific cytotoxic T lymphocytes
Definition
A population of autologous cytotoxic lymphocytes (CTLs) specifically reactive to the herpes virus cytomegalovirus (CMV) with potential immunomodulating and antiviral activities. Upon administration with the autologous CMV-specific CTLs, these CTLs lyse CMV-infected cells, thereby preventing or decreasing the occurrence of CMV viral disease, or reducing the amount of antiviral drug therapy needed to eradicate CMV.