Single Biggest Cancer Dictionary in the World
What is
autologous anti-PD-1 antibody-activated tumor-infiltrating lymphocytes
?Pronunciation: /autologous* ˈænˌti pd* wən ˈæntɪˌbɑdi ˈæktɪˌveɪtɪd ˈtumər ˌɪnˈfɪlˌtreɪtɪŋ ˈlɪmfəˌsaɪts/
autologous anti-PD-1 antibody-activated tumor-infiltrating lymphocytes
Definition
A preparation of autologous tumor infiltrating lymphocytes (TILs) activated by an anti-programmed cell death protein 1 (PD1) antibody, with potential immunomodulating activity. The autologous TILs are isolated from an autologous tumor sample and ex-vivo activated in the presence of anti-PD-1 antibody. Upon infusion of the autologous anti-PD1 antibody-activated TILs back into the patient, the cells specifically target and kill the patient’s tumor cells.