Single Biggest Cancer Dictionary in the World
What is autologous anti-gp100:154-162 TCR tumor infiltrating lymphocytes?
Pronunciation: /autologous* ˈænˌti gp* wən ˈhənərd wən ˈhənərd ənd fifty-four* wən ˈhənərd ənd sixty-two* tcr* ˈtumər ˌɪnˈfɪlˌtreɪtɪŋ ˈlɪmfəˌsaɪts/
autologous anti-gp100:154-162 TCR tumor infiltrating lymphocytes
Definition
A preparation of human tumor infiltrating lymphocytes (TILs) isolated from a melanoma patient and engineered to encode a T-cell receptor (TCR) specific for the amino acid 154 through 162 of the melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activities. Upon intravenous administration, the autologous anti-gp100:154-162 TCR TILs may recognize and halt the growth of gp100-expressing melanoma cells.