Single Biggest Cancer Dictionary in the World
What is
At 211 monoclonal antibody 81C6
?Pronunciation: /æt tu ˈhənərd ənd ˈilɛvən ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi eighty-one* si sɪks/
At 211 monoclonal antibody 81C6
Definition
A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb) 81C6 labeled with an alpha-emitting radionuclide Astatine 211 (At-211), with imaging and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix antigen tenascin (hexabrachion), which is up-regulated in gliomas and other cancers. Using MoAb 81C6 as a carrier for At-211 results in the targeted imaging and/or destruction of cells expressing tenascin.