Single Biggest Cancer Dictionary in the World
What is
anti-ANG2 monoclonal antibody MEDI-3617
?Pronunciation: /ˈænˌti æŋ tu ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi ˈmɛdi θri ˈθaʊzənd, sɪks ˈhənərd ənd ˈsɛvənˈtin/
anti-ANG2 monoclonal antibody MEDI-3617
Definition
A fully human IgG1 monoclonal antibody against angiopoietin 2 (ANG2), with potential antiangiogenic activity. Anti-ANG2 monoclonal antibody MEDI-3617 binds to Ang2 and interferes with the interaction between Ang2 and its receptor TEK tyrosine kinase (Tie2), thereby resulting in the disruption of vascular remodeling. This may inhibit angiogenesis and may eventually lead to an inhibition of tumor cell proliferation.