Single Biggest Cancer Dictionary in the World
What is androgen receptor degrader CC-94676?
Pronunciation: /androgen* riˈsɛptər degrader* ˈsiˈsi ninety-four* ˈθaʊzənd, sɪks ˈhənərd ənd seventy-six*/
androgen receptor degrader CC-94676
Definition
An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon administration, AR degrader CC-94676 causes degradation of AR, prevents AR-mediated signaling and inhibits the proliferation of AR-overexpressing tumor cells. AR plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC).