Single Biggest Cancer Dictionary in the World
What is allogeneic GM-CSF-secreting breast cancer vaccine?
Pronunciation: /allogeneic* gm* csf* secreting* brɛst ˈkænsər ˌvækˈsin/
allogeneic GM-CSF-secreting breast cancer vaccine
Definition
An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens.