Single Biggest Cancer Dictionary in the World
What is allogeneic CD34-positive E-rosetted T-cell depleted peripheral blood stem cells?
Pronunciation: /allogeneic* ˈsiˈdi thirty-four* ˈpɑzətɪv i rosetted* ti sɛl dɪˈplitɪd pərˈɪfərəl bləd stɛm sɛlz/
allogeneic CD34-positive E-rosetted T-cell depleted peripheral blood stem cells
Definition
A preparation of CD34+ selected peripheral blood stem cells (PBSCs) that are depleted of T cells via erythrocyte rosetting (E-rosetting) and intended for allogeneic stem cell transplant. Administration of this particular preparation of CD34+E- T-cell depleted PBSCs may potentially reduce the occurrence of graft-versus-host disease (GvHD) without increasing the risk of graft failure or poor graft function.