Single Biggest Cancer Dictionary in the World

What is

18F-fluoromisonidazole

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Pronunciation: /ˈeɪˈtin ɛf fluoromisonidazole*/

18F-fluoromisonidazole

Definition

A radiofluorinated 2-nitroimidazole derivate with hypoxia-specific tracer activity. Misonidazole is reduced under hypoxic conditions and in reduced form covalently binds to macromolecules in hypoxic cells. 18F (fluorine-18) radiofluorination of misonidazole to form 18F-fluoromisonidazole allows radioisotopic imaging of reduced misonidazole bound to macromolecules in hypoxic cells.