Single Biggest Cancer Dictionary in the World
What is TPI 287?
Pronunciation: /tpi* tu ˈhənərd ənd eighty-seven*/
TPI 287
Definition
A synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis.