Single Biggest Cancer Dictionary in the World
What is iodine I 131 monoclonal antibody muJ591?
Pronunciation: /ˈaɪəˌdaɪn aɪ wən ˈhənərd ənd thirty-one* ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi muj* faɪv ˈhənərd ənd ninety-one*/
iodine I 131 monoclonal antibody muJ591
Definition
A radioimmunoconjugate of a mouse monoclonal antibody (MoAb) J591 labeled with Iodine 131 (I-131). MoAb muJ591 recognizes the extracellular domain of the prostate-specific membrane antigen (PSMA) and reacts with tumor vascular endothelium. Using MoAb muJ591 as a carrier for I-131 results in the targeted imaging and/or destruction of cells overexpressed PSM.