Definition

A radioconjugate containing a folic acid receptor (FR; folate receptor) tracer labeled with fluorine F 18, with potential use for FR-expressing tumor imaging using positron emission tomography (PET). Upon administration of fluorine F 18-azafol, the azafol moiety selectively targets and binds to FR. This allows the visualization of tumor cells expressing FR using PET. FR is overexpressed on certain tumor cell types.