Single Biggest Cancer Dictionary in the World
What is deoxycytidine analogue TAS-109?
Pronunciation: /deoxycytidine* ˈænəˌlɔg tas* wən ˈhənərd ənd naɪn/
deoxycytidine analogue TAS-109
Definition
An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.