Definition

Daflon 500 is a phlebotonic drug and a vascular protecting agent. It is reported to improve microcirculation in chronic venous insufficiency by improvement of venous tone, inhibition of prostaglandin synthesis, protection against free radicals, activation of the complement system, and increased lymphatic drainage. This results in reduced venous capacitance, distensibility, and emptying time; reduced capillary permeability; and increased capillary resistance. (Angiology 1994 Jun;45(6):419-2)