Single Biggest Cancer Dictionary in the World
What is anti-ganglioside GM2 monoclonal antibody BIW-8962?
Pronunciation: /ˈænˌti ganglioside* gm* tu ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi biw* eɪt ˈθaʊzənd, naɪn ˈhənərd ənd sixty-two*/
anti-ganglioside GM2 monoclonal antibody BIW-8962
Definition
A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.