Definition

A breast cancer vaccine consisting of recombinant human alpha-lactalbumin (aLA), with potential immunostimulatory and antineoplastic activities. Upon administration, aLA breast cancer vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells that express the aLA protein, resulting in tumor cell lysis. aLA is expressed in many types of breast cancer, including triple negative breast cancer (TNBC), while normally present in healthy breast tissues only during lactation.