Definition

A combination of two drugs used alone or with bevacizumab to treat adults with certain types of colorectal cancer, stomach cancer, or gastroesophageal junction cancer. It is used in patients whose cancer has spread to other parts of the body and has already been treated with other anticancer treatments. It is also being studied in the treatment of other types of cancer. Trifluridine and tipiracil hydrochloride stops cells from making DNA, which may help keep cancer cells from growing and may kill them. It is a type of antimetabolite and a type of thymidine phosphorylase inhibitor. Also called Lonsurf.