Definition

A chronic condition marked by extreme swelling in an arm, leg, or other part of the body caused by a buildup of lymph in the tissues. The skin of the affected area usually feels hard and thick and may be darker in color. There may also be decreased mobility in the affected area. Stage III lymphedema can occur when lymph vessels or nodes become damaged or blocked, which affects the flow of lymph in the body. This is most commonly caused by cancer or cancer treatment, such as surgery or radiation therapy. Stage III lymphedema is considered the most advanced stage of lymphedema. Also called lymphostatic elephantiasis.