Single Biggest Cancer Dictionary in the World

What is sinusoidal obstruction syndrome?

Pronunciation: /ˈsaɪnəˌsɔɪdəl əbˈstrəkʃən ˈsɪnˌdroʊm/

sinusoidal obstruction syndrome

Definition

A condition in which some of the veins in the liver are blocked. This causes a decrease in blood flow inside the liver and may lead to liver damage. Signs and symptoms include weight gain, yellowing of the skin and whites of the eyes, dark-colored urine, and increased liver size. It may occur at some point in time after radiation therapy to the liver and bile ducts or after high-dose anticancer drugs were given before a stem cell transplant. Also called hepatic veno-occlusive disease.