Definition

A drug used to treat certain types of non-small cell lung cancer in adults and certain types of thyroid cancer or other solid tumor in adults and children aged 2 years and older. It is used in patients whose cancer has an abnormal RET gene. It is also being studied in the treatment of other types of cancer. Selpercatinib blocks certain proteins, including those made by the RET fusion gene or the mutated RET gene. Blocking these proteins may help keep cancer cells from growing. Selpercatinib is a type of tyrosine kinase inhibitor. Also called Retevmo.