Definition

A condition in which there is a lower-than-normal number of red and white blood cells and platelets in the blood. Pancytopenia occurs when there is a problem with the blood-forming stem cells in the bone marrow. Signs and symptoms include fatigue, weakness, dizziness, trouble breathing, fast heartbeat, fever, pale skin, purple or red spots on the skin, rash, easy bruising, and abnormal bleeding. Pancytopenia may be caused by certain autoimmune, bone marrow, or genetic disorders. It may also be caused by infection, poor nutrition, pregnancy, cancer treatment (such as chemotherapy or radiation therapy), or exposure to certain toxins, chemicals, or medicines.