Single Biggest Cancer Dictionary in the World

What is

NEDD8-activating enzyme inhibitor

?

Pronunciation: /nɛd eɪt ˈæktəˌveɪtɪŋ ˈɛnˌzaɪm ˌɪnˈhɪbətər/

NEDD8-activating enzyme inhibitor

Definition

A substance that blocks an enzyme called NEDD8-activating enzyme (NAE). NAE is involved in important cell functions, such as cell division. Blocking NAE may help keep cancer cells from growing and may kill them. Some NEDD8-activating enzyme inhibitors are being studied in the treatment of cancer. They are a type of targeted therapy. Also called NAE inhibitor.