Definition

A drug used to treat adults with certain types of B-cell non-Hodgkin lymphoma that relapsed (came back) or did not get better after treatment with at least two other types of systemic therapy. It is also being studied in the treatment of other types of cancer. Loncastuximab tesirine contains a monoclonal antibody that binds to a protein called CD19, which is found on some lymphoma cells. It also contains an anticancer drug, which may help kill cancer cells. Loncastuximab tesirine is a type of antibody-drug conjugate. Also called Zynlonta.