Definition

A drug used to treat adults with intermediate-risk or high-risk myelofibrosis (MF), including primary MF, post-polycythemia vera MF, and post-essential thrombocythemia MF. It is also being studied in the treatment of other conditions. Inrebic blocks JAK2 and other proteins, which may help keep abnormal blood cells or cancer cells from growing. It is a type of tyrosine kinase inhibitor. Also called fedratinib hydrochloride.