Definition

A drug used to treat adults with cutaneous T-cell lymphoma that has already been treated with at least one other type of systemic therapy. It is also being studied in the treatment of other types of cancer. FR901228 blocks certain enzymes needed for cell division and may kill cancer cells. It is a type of depsipeptide and a type of histone deacetylase inhibitor. Also called Istodax and romidepsin.