Definition

A gene that makes a protein that may help control cell growth and other important cell functions. Mutated (changed) forms of the folliculin gene may increase the growth of abnormal cells. The mutated folliculin gene has been found in an inherited condition called Birt-Hogg-Dube syndrome (BHDS). Patients with BHDS have an increased risk of kidney cancer and tumors of the skin and lungs. The folliculin gene is a type of tumor suppressor gene. Also called FLCN gene.