Definition

A large network of proteins and other molecules that surround, support, and give structure to cells and tissues in the body. The extracellular matrix helps cells attach to, and communicate with, nearby cells, and plays an important role in cell growth, cell movement, and other cell functions. The extracellular matrix is also involved in repairing damaged tissue. Abnormal changes in the extracellular matrix may lead to the development of certain diseases, such as cancer. The extracellular matrix of cancer cells can affect how they grow and spread. Also called ECM.