Definition

A gene that makes a protein that is involved in cell growth and cell survival. Mutated (changed) forms of the ERBB1 gene and protein have been found in some types of cancer, including non-small cell lung cancer. These changes may cause cancer cells to grow and spread in the body. Checking for changes in the ERBB1 gene in tumor tissue may help plan cancer treatment. Also called EGFR gene, epidermal growth factor receptor gene, and HER1 gene.