Single Biggest Cancer Dictionary in the World

What is single nucleotide variant?

Pronunciation: /ˈsɪŋgəl ˈnukliəˌtaɪd ˈvɛriənt/

single nucleotide variant

Definition

A DNA sequence variation that occurs when a single nucleotide (adenine, thymine, cytosine, or guanine) in the genome sequence is altered. Single nucleotide variants may be rare or common in a population. Sometimes single nucleotide variants are referred to as single nucleotide polymorphisms if they are present in at least 1% of the population. Also called SNV.