Single Biggest Cancer Dictionary in the World

What is

Z-360

?

Pronunciation: /zi θri ˈhənərd ənd ˈsɪksti/

Z-360

Definition

A selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells.