Single Biggest Cancer Dictionary in the World

What is

vitamin K1-containing urea skin cream

?

Pronunciation: /ˈvaɪtəmən keɪ wən kənˈteɪnɪŋ jərˈiə skɪn krim/

vitamin K1-containing urea skin cream

Definition

A topical cream containing urea and 0.1% vitamin K1 (phytomenadione) with topical epidermal growth factor receptor (EGFR)-activating activity. Upon application of vitamin K1-containing urea skin cream, vitamin K1 may locally activate EGFR, thereby abrogating EGFR inhibition in the skin caused by systemic EGFR inhibiting agents. This may help inhibit the acne-like skin rash induced by EGFR antagonists. EGFR, a tyrosine kinase, plays a key role in maintaining epidermal integrity.