Single Biggest Cancer Dictionary in the World
What is tyrosine kinase inhibitor OSI-930?
Pronunciation: /tyrosine* kinase* ˌɪnˈhɪbətər osi* naɪn ˈhənərd ənd ˈθərˌdi/
tyrosine kinase inhibitor OSI-930
Definition
A selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers.