Single Biggest Cancer Dictionary in the World

What is

tositumomab

?

Pronunciation: /tositumomab*/

tositumomab

Definition

A murine IgG2 monoclonal antibody directed against the CD20 antigen, found on the surface of B cells. Tositumomab binds to the CD20 surface membrane antigen, resulting in apoptosis, and may stimulate antitumoral cell-mediated and/or antibody-dependent cytotoxicity.