Definition

A topical preparation containing an ethanol extract of Piper crocatum (red betel leaves), with potential anti-inflammatory and anti-oxidant activities. Red betel leaf contains flavonoids, alkaloids, polyphenolates, tannins, and essential oils. Upon topical application of P. crocatum extract, the active ingredients may exert anti-inflammatory and anti-oxidant effects on the skin, and may treat anogenital warts through as of yet not elucidated mechanisms of action.