Single Biggest Cancer Dictionary in the World
What is SERD SHR9549?
Pronunciation: /serd* shr* naɪn ˈθaʊzənd, faɪv ˈhənərd ənd forty-nine*/
SERD SHR9549
Definition
An orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SHR9549 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells.