Single Biggest Cancer Dictionary in the World
What is selective estrogen receptor degraderLSZ102?
Pronunciation: /səˈlɛktɪv ˈɛstrəʤən riˈsɛptər degraderlsz* wən ˈhənərd ənd tu/
selective estrogen receptor degraderLSZ102
Definition
A selective estrogen receptor (ER) degrader (SERD), with potential antineoplastic activity. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells.