Single Biggest Cancer Dictionary in the World
What is
selective estrogen receptor degrader SRN-927
?Pronunciation: /səˈlɛktɪv ˈɛstrəʤən riˈsɛptər degrader* srn* naɪn ˈhənərd ənd twenty-seven*/
selective estrogen receptor degrader SRN-927
Definition
An orally available, nonsteroidal selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, SERD SRN-927 specifically binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells.