Single Biggest Cancer Dictionary in the World
What is rituximab conjugate CON-4619?
Pronunciation: /rituximab* ˌkɑnʤəˈgeɪt kɑn fɔr ˈθaʊzənd, sɪks ˈhənərd ənd ˈnaɪnˈtin/
rituximab conjugate CON-4619
Definition
A proprietary conjugate of rituximab, a recombinant chimeric murine/human antibody directed against the CD20 antigen, with potential antineoplastic activity. Upon administration of the rituximab conjugate CON-4619, the rituximab moiety targets and binds to CD20, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells.