Single Biggest Cancer Dictionary in the World
What is recombinant tumor necrosis factor family protein?
Pronunciation: /rɪˈkɑmbɪnənt ˈtumər nəˈkroʊsəs ˈfæktər ˈfæməli ˈproʊˌtin/
recombinant tumor necrosis factor family protein
Definition
A recombinant therapeutic agent which is chemically identical to or similar to one of a number of endogenous tumor necrosis factor (TNF) proteins. TNF family cytokines bind to and activate specific cell-surface receptors, thereby mediating inflammatory processes, cell proliferation, immunity, angiogenesis, and tumor cell cytotoxicity. One primary antitumor effect of TNFs involves stimulation of T cell-mediated antitumor cytotoxicity.