Single Biggest Cancer Dictionary in the World
What is radium Ra 224-labeled calcium carbonate microparticles?
Pronunciation: /ˈreɪdiəm rɑ tu ˈhənərd ənd tˈwɛntiˌfɔr ˈleɪbəld ˈkælsiəm ˈkɑrbəˌneɪt microparticles*/
radium Ra 224-labeled calcium carbonate microparticles
Definition
A radiopharmaceutical composed of biodegradable calcium carbonate microspheres labeled with the alpha-emitting radioisotope radium Ra 224, with antineoplastic activity. Upon intraperitoneal (IP) administration of the radium Ra 224-labeled calcium carbonate microparticles, Ra 224 kills tumor cells through local emission of high energy alpha particles, causing DNA double-strand breaks. The short range effects of alpha emission allows for localized DNA damage with limited toxicity to nearby healthy tissue.