Definition

The hydrochloride salt form of the free base form of BEBT-908, an inhibitor of both phosphoinositide 3-kinase (PI3K) and histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon administration, PI3K/HDAC inhibitor BEBT-908 binds to and inhibits the activity and mediated signaling of both PI3K and HDAC. In addition, BEBT-908 may also inhibit other signaling pathways. This may prevent growth of PI3K and/or HDAC-expressing tumor cells.