Single Biggest Cancer Dictionary in the World
What is oncolytic Vaccinia virus PF-07263689?
Pronunciation: /oncolytic* vəˈʧiniə ˈvaɪrəs pf* ˈsɛvən ˈmɪljən, tu ˈhənərd ənd sixty-three* ˈθaʊzənd, sɪks ˈhənərd ənd eighty-nine*/
oncolytic Vaccinia virus PF-07263689
Definition
An engineered oncolytic vaccinia virus (VV), with potential immunomodulating and antineoplastic activities. Upon administration of oncolytic VV PF-07263689, the virus preferentially targets and infects tumor cells, thereby causing oncolysis. In turn, the lysed tumor cells release various tumor-associated antigens (TAAs), which induce an immune response against the tumor cells. This further kills tumor cells.