Single Biggest Cancer Dictionary in the World

What is

oncolytic Newcastle disease virus

?

Pronunciation: /oncolytic* ˈnuˌkæsəl dɪˈziz ˈvaɪrəs/

oncolytic Newcastle disease virus

Definition

An oncolytic viral agent containing the oncolytic, live-attenuated strain of the paramyxovirus Newcastle disease virus (NDV), with potential antineoplastic activity. Upon administration, NDV specifically infects and replicates in cancer cells. This may result in a direct cytotoxic effect involving the lysis of tumor cells via apoptotic mechanisms and may eventually lead to an inhibition of cancer cell proliferation.