Single Biggest Cancer Dictionary in the World
What is
methoxyamine
?Pronunciation: /methoxyamine*/
methoxyamine
Definition
An orally bioavailable small molecule inhibitor with potential adjuvant activity. Methoxyamine covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. This agent may potentiate the anti-tumor activity of alkylating agents.