Single Biggest Cancer Dictionary in the World
What is
melphalan
?Pronunciation: /melphalan*/
melphalan
Definition
A phenylalanine derivative of nitrogen mustard with antineoplastic activity. Melphalan alkylates DNA at the N7 position of guanine and induces DNA inter-strand cross-linkages, resulting in the inhibition of DNA and RNA synthesis and cytotoxicity against both dividing and non-dividing tumor cells.